Exam Preview

Genetics & Hearing, presented in partnership with Salus University

---

1.  In this mode of inheritance, affected fathers cannot pass the trait: X-Linked Y-Linked Mitochondria Autosomal Recessive

2.  Which one of these is an acrocentric chromosome? 18 11 20 14

3.  Which one of the following syndromes/illnesses is an autosomal dominant condition? Waardenberg syndrome Marfan's Syndrome Trisomy 13 Syndrome Tay Sachs

4.  The following Pedigree represents (Click here to see image): Mitochondrial inheritance Y linked Autosomal recessive X linked

5.  Due to _______________, for some genes, the copy inherited from the mother functions differently from the copy inherited from the father. Variable Expressivity Mosaicism Imprinting Uniparental disomy

6.  The first published description of a gene for nonsyndromic deafness was for: Connexin 30 Connexin 26 30delG 35delG

7.  What does this pedigree legend mean (Click here to see image)? Second marriage or relationship Non-identical twins Infertile Consanguinity

8.  Aminoglycoside induced hearing loss is commonly seen in cases with: Mitochondrial Disease Pendred Syndrome Alport Syndrome Apert Syndrome

9.  Heterochromia iridium is a major characteristic of: Alport Syndrome Usher Syndrome Waardenburg Syndrome Pendred Syndrome

10.  Perilympatic Gusher is potentially associated with: Endolymphatic Hydrops Otosclerosis Enlarged Vestibular Aqueduct Pendred Syndrome

11.  For monogenic prelingual hearing loss, _______ is the most common mode of inheritance? Y-Linked X-Linked Autosomal Dominant Autosomal Recessive

12.  In addition to hearing loss, many affected individuals with this syndrome have pigmentation disorders: Usher Syndrome Pendred Syndrome Waardenburg Syndrome Stickler Syndrome

13.  In addition to hearing loss, many affected individuals with this syndrome have visual disorders: Usher Syndrome Pendred Syndrome Waardenburg Syndrome Apert Syndrome

14.  Which one of the following genetic syndromes/diseases may be associated with Auditory Neuropathy? Marfan Syndrome Charcot-Marie-Tooth Disease Asperger's Syndrome Tekin Syndrome

15.  Enlarged Vestibular Aqueduct is a defect that is found in which one of the following syndrome? Alport Syndrome Apert's Syndrome Stickler's Syndrome Pendred Syndrome